Neonatal lupus erythematous – A report of three cases

  • Punit S Chhajed
  • S V Savaskar
  • N S Bhori
  • S T Bandichhode
Keywords: Autoimmune, Congenital heart block, Neonatal lupus, Raccoon eyes, SLE

Abstract

Neonatal lupus erythematosus (NLE) is a rare acquired autoimmune disorder clinically characterized by skin lesions that resemble those of subacute or discoid lupus erythematosus and/or congenital heart bock. Skin and cardiac manifestations coexist only in 10% of the patients. It is caused by transplacental passage of maternal autoantibodies, usually anti-Ro/SS-A and /or anti-La/SS-B and less commonly anti-U1 ribonucleoprotein. Mothers of the infants with NLE are either asymptomatic or diagnosed with autoimmune disease. We describe 3 neonates with clinical and immunological findings compatible with NLE, their progress and outcome.

Published
2017-11-22
How to Cite
Chhajed, P., Savaskar, S., Bhori, N., & Bandichhode, S. (2017, November 22). Neonatal lupus erythematous – A report of three cases. Indian Journal of Child Health, 4(4), 631-634. Retrieved from http://atharvapub.net/index.php/IJCH/article/view/383
Section
Case Reports