McCune-Albright syndrome without endocrine dysfunction: Case report in a young boy

  • Elkashif Sami
  • Agrawal Pankaj
Keywords: Fibrous dysplasia, McCune-Albright syndrome, Polyostotic

Abstract

The McCune-Albright syndrome (MAS) is a sporadic rare disease characterized by a triad of physical signs: Café-au lait spots, polyostotic fibrous dysplasia, and autonomous endocrine hyperfunction. Based on the studies, it can be concluded that this syndrome is caused by mutations that happen in the gene: GNAS1. A small number, but not all, of the patient’s cells contain this faulty gene (mosaicism). MAS is predominantly observed in girls and is rarely reported in males. We report a 5-year-old boy with café-au-lait spots, polyostotic fibrous dysplasia, and without any endocrine dysfunction.

Published
2017-11-22
How to Cite
Sami, E., & Pankaj, A. (2017, November 22). McCune-Albright syndrome without endocrine dysfunction: Case report in a young boy. Indian Journal of Child Health, 4(4), 649-651. Retrieved from http://atharvapub.net/index.php/IJCH/article/view/390
Section
Case Reports