Rare association of celiac disease with congenital heart disease

  • Rashi Bhargava
  • Aaradhana Singh
  • Anju Aggarwal
  • Manish Narang


Celiac disease (CD) is an autoimmune enteropathy caused by exposure to dietary gluten in genetically predisposed individuals. CD is a multisystem disease involving gastrointestinal, hepatobiliary, nervous, hematologic, and cardiovascular systems. Few associations of congenital heart disease have been reported with CD. We report a case of an 8-year-old female, who was presented to the hospital with severe anemia and undernutrition. She had severe pallor, clubbing, hepatomegaly, and a Grade Ш systolic ejection murmur. Echocardiography revealed a large ostium secundum type of atrial septal defect and patent ductus arteriosus. The increased levels of serum IgA anti-tissue transglutaminase (anti-TTG) antibody have arisen suspicion of CD, which was confirmed after the histopathological study of the duodenal biopsy. We are reporting this case to highlight the rare association of the CD with congenital heart disease.

Keywords: Atrial septal defect, Celiac disease, Congenital heart disease, Echocardiography, Patent ductus arteriosus
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How to Cite
Bhargava, R., Singh, A., Aggarwal, A., & Narang, M. ( ). Rare association of celiac disease with congenital heart disease. Indian Journal of Child Health, 6(5), 255-256. https://doi.org/https://doi.org/10.32677/IJCH.2019.v06.i05.016
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