Recombinant activated factor VII for refractory bleeding during pediatric spinal tumor surgery: A case report

  • Rebai Lotfi
  • Boussaidi Ines
  • Daghmouri Aziz
  • Ghader Ghassen

Abstract

Bleeding complications constitute a particular challenge in neurosurgical procedures especially in children and may be life-threatening. We report the case of a 5-month-old boy to whom recombinant activated factor VII was given at doses of 90 μg/kg of body weight for the control of refractory perioperative bleeding during spinal neurofibromas surgery. Conventional treatment with fresh-frozen plasma, platelet concentrates, and fibrinogen concentrate failed to control hemorrhage. Recombinant activated factor administration resulted in decreased bleeding, hemodynamic stabilization, and improved surgical hemostasis.

Keywords: Refractory bleeding, Spinal tumor, Children, Recombinant activated factor VII
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How to Cite
Lotfi, R., Ines, B., Aziz, D., & Ghassen, G. ( ). Recombinant activated factor VII for refractory bleeding during pediatric spinal tumor surgery: A case report. Indian Journal of Case Reports, 4(6), 444-446. https://doi.org/https://doi.org/10.32677/IJCR.2018.v04.i06.011
Section
Case Report