Clinical profile of different type of tuberculosis in hospitalized children in tertiary care center

  • Rashmi S Thanvi
  • Ashish Jain
  • Shital M Patel
  • Nehal H Patel
  • Geet Gunjana
  • Krina Patel


Background: Since the implementation of directly observed treatment short (DOTS) program, the prevalence, clinical profile,
and risk factors of pulmonary and non-pulmonary tuberculosis (TB) necessitating hospitalization in pediatric patients are not
evaluated extensively. Materials and Methods: We designed a prospective observational study to evaluate the clinical profile of
different types of TB in hospitalized children <12 years old. Different types of TB in children hospitalized from 1st January 2013
to 30th June 2014 were recorded. Detailed clinical history, clinical examination findings, diagnostic methods, and treatment of
these cases were analyzed by age groups and types of TB. Results: During the study period, 150 (2.8% of total admission) patients
with TB were admitted in our institute. 87 (58%) patients were <5 years old, and 92 (61.33%) children were male. 140 (93.33%)
children were malnourished. The clinical profile of TB included neuro TB in 78 (37.32%), pulmonary in 67 (32.05), abdominal
in 27 (12.91%), and disseminated in 27 (12.91%) patients. Less than half of children with neuro TB and disseminated TB were
immunized with Bacillus calmette-guerin (BCG). Conclusion: Despite aggressive DOTS implementation, the prevalence of TB,
particularly, non-pulmonary TB in children is quite alarming. All the variants of TB are prevalent in the children. The neuro TB and
the pulmonary TB dominate in the hospitalized cases. Younger age, lack of protection of BCG vaccination, and malnutrition are
the main risk factors in childhood TB.

Keywords: Bacillus calmette-guerin vaccination, Childhood tuberculosis, Malnutrition
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How to Cite
Thanvi, R., Jain, A., Patel, S., Patel, N., Gunjana, G., & Patel, K. (2017). Clinical profile of different type of tuberculosis in hospitalized children in tertiary care center. Indian Journal of Child Health, 4(4), 530-534. Retrieved from
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