Postpartum pituitary necrosis: A report of 2 autopsy cases

  • Shruti Chandrakar
  • Anitha Padmanabhan


Major hormonal changes emerge during pregnancy. The pituitary gland is one of the most affected organs with altered anatomy and
physiology. Sheehan’s syndrome also known as Simmonds’s syndrome or postpartum anterior pituitary necrosis is due to ischemic
necrosis secondary to blood loss and hypovolemic shock after child birth. We report two autopsy cases of postpartum anterior
pituitary necrosis with their clinical correlation. Histopathological examination of pituitary in both the cases showed extensive areas
of coagulative necrosis involving the anterior pituitary. Both the cases were associated with indirect causes of maternal deaths like
infectious etiology.

Keywords: Autopsy, Maternal Death, Pituitary, Sheehan’s
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How to Cite
Chandrakar, S., & Padmanabhan, A. (2017). Postpartum pituitary necrosis: A report of 2 autopsy cases. Indian Journal of Case Reports, 3(4), 184-186. Retrieved from
Case Report